Method of producing partially purified extracellular metabolite products fromBacillus coagulansand biological applications thereof
| Filling date | : | July 20, 2016 |
| Issue date | : | June 20, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: The antimicrobial effect of extracellular metabolite composition from Bacillus coagulans MTCC 5856 and composition comprising from about 61% w/w of thymol, 38% of monolaurin and 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis is described.
Method of producing partially purified extracellular metabolite products fromBacillus coagulansand biological applications thereof
| Filling date | : | July 20, 2016 |
| Issue date | : | June 20, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: The antimicrobial effect of extracellular metabolite composition from Bacillus coagulans MTCC 5856 is described.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | July 20, 2016 |
| Issue date | : | May 02, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Process of inhibiting microbial biofilm formation using extracellular metabolite composition from Bacillus coagulans MTCC 5856 and composition comprising from about 61% w/w of thymol, about 38% w/w of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis is described.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | December 19, 2014 |
| Issue date | : | March 21, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Method of extracting a partially purified extracellular metabolite composition from Bacillus coagulans MTCC 5856 and its antimicrobial effects thereof are described.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | December 24, 2014 |
| Issue date | : | April 14, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | December 24, 2014 |
| Issue date | : | April 28, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: The invention proposed the method of obtaining extracellular metabolite preparation of probiotic bacterial strain Bacillus coagulans MTCC 5856, methods for controlling the growth and viability of microbial pathogens, the method for inhibiting the formation of microbial biofilm formation, as well as a method for preventing the further accumulation of biofilm Streptococcus mutans and the resulting reduction in pH.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | December 24, 2014 |
| Issue date | : | August 17, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | December 24, 2014 |
| Issue date | : | October 31, 2017 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | August 4, 2015 |
| Issue date | : | January 11, 2018 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | August 4, 2015 |
| Issue date | : | August 29, 2018 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: The invention in general relates to the anti-microbial effects of probiotic preparations. More specifically, the present invention relates to (1) a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC37-01 (Deposited in the Microbial Type Culture Collection and GeneBank and was assigned the strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050 and (2) the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens. The extracellular metabolite preparation is also shown to inhibit microbial biofilm formation in a synergistic manner.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | August 4, 2015 |
| Issue date | : | September 18, 2018 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.
Method of producing partially purified extracellular metabolite products from Bacillus coagulans and biological applications thereof
| Filling date | : | July 30, 2015 |
| Issue date | : | November 27, 2018 |
| Inventors | : | Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali |
Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.